Chronic diseases which compromise the immune system (diabetes, dialysis, etc.)
Reduced immune response (age > 50)
• Half of the female population are of reproductive age: 1.95 billion women globally • Epidemiology studies of mTSS performed confirm the mTSS association with tampon use and case numbers being 1 2/100K in developed countries • Toxic shock syndrome can lead to death in 30% to 70% of cases