publications
Functional and Immunological Studies Revealed a Second Superantigen Toxin in Staphylococcal Enterotoxin
Toxins (Basel). 2022 Aug 29;14(9):595. doi: 10.3390/toxins14090595. Functional and Immunological Studies Revealed a Second Superantigen Toxin in Staphylococcal Enterotoxin C Producing Staphylococcus aureus Strains. Andreas Roetzer , Nina Model , Jakob Laube, Yvonne Unterhumer, Guenter Haller, Martha M Eibl.
High Titer Persistent Neutralizing Antibodies Induced by TSST-1 Variant Vaccine Against Toxic Shock Cytokine Storm
Toxins (Basel). 2020 Oct 2;12(10):640. doi: 10.3390/toxins12100640. High Titer Persistent Neutralizing Antibodies Induced by TSST-1 Variant Vaccine Against Toxic Shock Cytokine Storm. Andreas Roetzer, Norbert Stich, Nina Model, Michael Schwameis, Christa Firbas, Bernd Jilma, Martha M Eibl.
Expert Rev Vaccines. 2017 Feb;16(2):81-83.doi: 10.1080/14760584.2017.1268921.Vaccine against toxic shock syndrome in a first-in-man clinical trial. Andreas Roetzer, Bernd Jilma, Martha M Eibl.
Enterotoxin Gene Cluster-Encoded SEI and SElN from Staphylococcus aureus Isolates are Crucial for the Induction of Human Blood Cell Proliferation and Pathogenicity in Rabbits
Toxins (Basel). 2016 Oct 28;8(11):314.doi: 10.3390/toxins8110314. Enterotoxin Gene Cluster-Encoded SEI and SElN from Staphylococcus aureus Isolates are Crucial for the Induction of Human Blood Cell Proliferation and Pathogenicity in Rabbits. Andreas Roetzer, Corina S Gruener, Guenter Haller, John Beyerly, Nina Model, Martha M Eibl.
Safety, tolerability, and immunogenicity of a recombinant toxic shock syndrome toxin (rTSST)-1 variant vaccine: a randomised, double-blind, adjuvant-controlled, dose escalation first-in-man trials
Lancet Infect Dis. 2016 Sep;16(9):1036-1044.doi: 10.1016/S1473-3099(16)30115-3. Safety, tolerability, and immunogenicity of a recombinant toxic shock syndrome toxin (rTSST)-1 variant vaccine: a randomised, double-blind, adjuvant-controlled, dose escalation first-in-man trial. Michael Schwameis, Bernhard Roppenser, Christa Firbas, Corina S Gruener, Nina Model, Norbert Stich, Andreas Roetzer, Nina Buchtele, Bernd Jilma, Martha M Eibl
Toxic shock syndrome toxin-1-mediated toxicity inhibited by neutralizing antibodies late in the course of continual in vivo and in vitro exposure
Toxins (Basel). 2014 May 30;6(6):1724-41.doi: 10.3390/toxins6061724. Toxic shock syndrome toxin-1-mediated toxicity inhibited by neutralizing antibodies late in the course of continual in vivo and in vitro exposure. Norbert Stich, Nina Model, Aysen Samstag, Corina S Gruener, Hermann M Wolf, Martha M Eibl.
Staphylococcal superantigen (TSST-1) mutant analysis reveals that t cell activation is required for biological effects in the rabbit including the cytokine storm.
Toxins (Basel). 2010 Sep;2(9):2272-88.doi: 10.3390/toxins2092272. Staphylococcal superantigen (TSST-1) mutant analysis reveals that t cell activation is required for biological effects in the rabbit including the cytokine storm. Norbert Stich, Martina Waclavicek, Nina Model, Martha M Eibl.
Analysis of the early response to TSST-1 reveals Vbeta-unrestricted extravasation, compartmentalization of the response, and unresponsiveness but not anergy to TSST-1.
J Leukoc Biol. 2009 Jan;85(1):44-54.doi: 10.1189/jlb.0108074. Analysis of the early response to TSST-1 reveals Vbeta-unrestricted extravasation, compartmentalization of the response, and unresponsiveness but not anergy to TSST-1. Martina Waclavicek, Norbert Stich, Ingrid Rappan, Helga Bergmeister, Martha M Eibl.
Epitope mapping of neutralizing TSST-1 specific antibodies induced by immunization with toxin or toxoids